I-LtrI / I-PanMI
Type
Chimera
Target Sequence
| -11 | -10 | -9 | -8 | -7 | -6 | -5 | -4 | -3 | -2 | -1 | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 |
| A | A | T | G | C | T | C | C | T | A | T | T | C | C | T | T | A | T | C | A | A | G |
FASTA Sequence
FPVQARNDNITPWWITGFADAESSFMLTVSKDSKRNTGWSVRPRFRIGLHNKDVSILKSIREYLGAGIITSDKDA
RIRFESLKELEVVINHFDKYPLITQKRADYLLFKKAFYLIKNKEHLTEEGLNQILTLKASLNLGLSEELKEAFPN
TIPAEKLLISGTILNPAWLSGFVSGEGCFSVVVFKSKTSKLGEAVKLSFILTQSNRDEYLIKSLIEYLGCGNTSL
DPRGTIDFKVTNFSSIKDIIVPFFIKYPLIGNKNLDFTDFCEVVRLMENKSHLTKEGLDQIKKIRNRMNTNRK
RIRFESLKELEVVINHFDKYPLITQKRADYLLFKKAFYLIKNKEHLTEEGLNQILTLKASLNLGLSEELKEAFPN
TIPAEKLLISGTILNPAWLSGFVSGEGCFSVVVFKSKTSKLGEAVKLSFILTQSNRDEYLIKSLIEYLGCGNTSL
DPRGTIDFKVTNFSSIKDIIVPFFIKYPLIGNKNLDFTDFCEVVRLMENKSHLTKEGLDQIKKIRNRMNTNRK
(-) Endonuclease Amino Acid Contact Modules
| Module | Amino Acid Contact Modules (?) |
| -11 → -9: | Asp 39, Lys 41, Arg 42, Asn 43, Thr 44, Gly 45, Ser 47 |
| -8 → -6: | Met 33, Thr 35, Ser 37, Arg 49, Arg 51, Ile 75, Thr 77, Arg 85, Glu 87 |
| -6 → -4: | Ser 31, Met 33, Arg 53, Gly 55, Thr 77, Arg 83, Arg 85 |
| -5 → -3: | Ser 31, Arg 53, Gly 55, Ile 80*, Asp 81*, Arg 83, Arg 85 |
(+) Endonuclease Amino Acid Contact Modules
| Module | Amino Acid Contact Modules (?) |
| +3 → +5: | Cys 179, Ser 181, Ile 201, Thr 203, Asp 227, Arg 229*, Tyr 231, Asp 233 |
| +4 → +6: | Ser 181, Val 183, Ser 199, Ile 201, Asn 223, Ser 225, Asp 227, Lys 235 |
| +6 → +8: | Val 183, Phe 185, Ala 195, Lys 197, Ser 199, Asn 223, Thr 237 |
| +9 → +11: | Phe 185, Ser 187, Thr 189*, Ser 190, Lys 191, Leu 192, Gly 193, Ala 195 |
Key
| Experiment | |
| Crystal Structure | |
| Sequence Alignment | |
| * | Uncertain |